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In addition, the increase in the phosphorylation of p38 MAPK was not statistically significant (Figure 6)

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Tesamorelin is a stabilized analog of endogenous GHRH that interacts with GHRH receptors to influence growth hormone signaling cascades, while Ipamorelin is a selective agonist of the ghrelin (GHS-R1a) receptor studied for its role in modulating growth hormone release without significant interaction with other hormonal pathways